Improved synthesis of N1-substituted orotic acid derivatives
نویسندگان
چکیده
منابع مشابه
Improved synthesis of N1-substituted orotic acid derivatives.
An improved method for the synthesis of N1-substituted orotic acid derivatives is reported. The method involves sequential incorporation of nitrogen atoms to the pyrimidine structure from simple starting materials and thus allows the synthesis of N1-substituted orotic acid derivatives with single 15N label at either N-1 or N-3.
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ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 2013
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2013.05.136